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CD49f has been identified as a marker for tumor-initiating cells (TICs) in hepatocellular carcinoma (HCC)
thereby acting as a tumor suppressor
and its expression can be modulated in different pathological conditions
Activation occurs via phosphorylation of IκBα at Ser32 and Ser36 followed by proteasome-mediated degradation that results in the release and nuclear translocation of active NF-κB [PMID: 7739562]
It can also serve as a reference marker for the prognosis of cancer patients
Human CDK2 ELISA Kit Size:96T CD49f has been identified asProduct Specification protein CDK2 Usage Sample collection preparation and preservation 1. Serum: Whole blood sample placed at room temperature 2 Hour or 4C Overnight after 1000g Centrifugation 20 Minutes, take the supernatant to detect. The blood collection tubes shall be disposable non pyrogenic, non endotoxin tubes. deposit 20C Or 80C Storage, avoid repeated freezing and thawing. 2. Plasma: Sample after collection 30 Within minutes 2 8C 1000g