(2010) Use of GM-CSF as an adjuvant with cancer vaccines: beneficial or detrimental
Programmed death ligand 1 (PD-L1) belongs to the B7 series and is a 33-kDa type 1 transmembrane glycoprotein that contains 290 amino acids with Ig-V and IgC domains in its extracellular region
with C-terminal Human IgG1 Fc MAQQCFHSEYFDSLLHACKPCHLRCSNPPATCQPYCDPSVTSSVKGTYTIEGRMDPKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
tumor metastasis and reduced patient survival
and an anchor molecule on circulating and disseminated tumor cells (CTCs/DTCs)
OSM(209aa) Protein, Human Size:100μg (2010) Use of GM-CSF asProduct Specification Species Human Synonyms OSM, Oncostatin M, MGC20461, OncoM Accession P13725 Amino Acid Sequence Ala26 Arg234 Expression System E. coli Molecular Weight 24kDa Purity >95% by SDS PAGE Endotoxin <1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized Powder Storage Buffer 20mM Tris, 150mM NaCl, pH8. 0, 1mM TCEP Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water after rapid